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1.
Bol. Hosp. Viña del Mar ; 78(1-2): 13-17, 2022.
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1398498

ABSTRACT

El encondroma protuberans (EP) es una forma rara de encondroma que muestra un crecimiento exofítico, fuera de los márgenes del hueso cortical. Se presenta el caso de una paciente de 4 años previamente sana que asistió en el servicio de urgencia con un aumento de volumen no doloroso en meñique izquierdo. La radiografía mostró una lesión radiolúcida expansiva en la falange proximal. Se complementa estudio con tomografía computarizada y resonancia magnética descubriéndose una lesión que comprometía el canal medular, con extensión más allá de la cortical y un aumento de intensidad de señal en secuencia T2 sugestiva de matriz condroide. El paciente fue sometido a escisión quirúrgica, curetaje e injerto óseo. El estudio histopatológico postquirúrgico confirmó el diagnóstico de encondroma. En este estudio se describió un caso de EP que involucra una falange de la mano. El estudio imagenológico, en particular las imágenes por resonancia magnética juegan un papel clave para un diagnóstico preciso previo al procedimiento quirúrgico.


Enchondroma protruberans (EP) is a rare form of enchondroma with exophytic growth outside the margins of cortical bone. We present the case of a previously healthy 4-year-old patient who attended the Emergency Department with painless enlargement of the left pinkie. The X-ray showed an expansive radiolucent lesion of the proximal phalanx. Further study with a computed tomography scan and magnetic resonance imaging revealed a lesion affecting the medullary cavity and extending beyond the cortical bone with an increase in signal strength in the T2 sequence suggestive of a chondroid matrix. The patient underwent surgical excision, curettage, and bone grafting. The post-surgical histopathological study confirmed the diagnosis of enchondroma. This study describes a case of EP involving a phalanx of the hand. The images, particularly those of the magnetic resonance imaging, played a key role in reaching an accurate diagnosis prior to surgery.

2.
Clinics ; 76: e2914, 2021. tab, graf
Article in English | LILACS | ID: biblio-1350607

ABSTRACT

OBJECTIVES: The aim of this study was to evaluate the role of amphiregulin protein, an epidermal growth factor receptor ligand, in cartilaginous tumors. METHODS: Amphiregulin expression was examined in 31 enchondromas and 67 chondrosarcomas using immunohistochemistry analysis. RESULTS: Overall, 15 enchondromas (48.40%) and 24 chondrosarcomas (35.82%) were positive for amphiregulin. According to the receiver operating characteristic curve test, no difference in amphiregulin expression was observed between enchondromas and low-grade chondrosarcomas (p=0.0880). Additionally, 39 lesions (16 in short bones, 13 in long bones, and 10 in flat bones) were positive for amphiregulin, exhibiting a higher percentage of positive cells (p=0.0030) and intensity of immunohistochemical expression (p=0.0055) in short bone lesions than in others. Among 25 enchondromas localized in short bones, 15 expressed amphiregulin; however, all 6 cases localized in long bones were negative for this marker (p=0.0177). CONCLUSIONS: Amphiregulin did not help in distinguishing enchondromas from low-grade chondrosarcomas. The present study is the first to document the expression of this immunohistochemical marker in enchondromas. Furthermore, amphiregulin expression in enchondromas was localized in short bones, indicating a phenotypic distinction from that in long bones. This distinction may contribute to an improved understanding of the pathogenesis of these lesions.


Subject(s)
Humans , Bone Neoplasms , Chondroma , Chondrosarcoma , Amphiregulin/genetics , Immunohistochemistry
3.
Journal of Southern Medical University ; (12): 483-490, 2020.
Article in Chinese | WPRIM | ID: wpr-828952

ABSTRACT

OBJECTIVE@#To develop and validate radiomics models based on non-enhanced magnetic resonance (MR) imaging for differentiating chondrosarcoma from enchondroma.@*METHODS@#We retrospectively evaluated a total of 68 patients (including 27 with chondrosarcoma and 41 with enchondroma), who were randomly divided into training group (=46) and validation group (=22). Radiomics features were extracted from TWI and TWI-FS sequences of the whole tumor by two radiologists independently and selected by Low Variance, Univariate feature selection, and least absolute shrinkage and selection operator (LASSO). Radiomics models were constructed by multivariate logistic regression analysis based on the features from TWI and TWI-FS sequences. The receiver-operating characteristics (ROC) curve and intraclass correlation coefficient (ICC) analyses of the radiomics models and conventional MR imaging were performed to determine their diagnostic accuracy.@*RESULTS@#The ICC value for interreader agreement of the radiomics features ranged from 0.779 to 0.923, which indicated good agreement. Ten and 11 features were selected from the TWI and TWI-FS sequences to construct radiomics models, respectively. The areas under the curve (AUCs) of TWI and TWI-FS models were 0.990 and 0.925 in training group and 0.915 and 0.855 in the validation group, respectively, showing no significant differences between the two sequence-based models (>0.05). In all the cases, the AUCs of the two radiomics models based on TWI and TWI-FS sequences and conventional MR imaging were 0.955, 0.901 and 0.569, respectively, demonstrating a significantly higher diagnostic accuracy of the two sequence-based radiomics models than conventional MR imaging (<0.01).@*CONCLUSIONS@#The radiomics models based on TWI and TWI-FS non-enhanced MR imaging can be used for the differentiation of chondrosarcoma from enchondroma.


Subject(s)
Humans , Chondroma , Chondrosarcoma , Magnetic Resonance Imaging , ROC Curve , Retrospective Studies
4.
Rev. bras. ortop ; 54(6): 714-720, Nov.-Dec. 2019. tab, graf
Article in English | LILACS | ID: biblio-1057963

ABSTRACT

Abstract Objective Enchondromas are the commonest tumors of the bones of the hand. Treatment approaches vary. The present article presents the characteristics of the tumors, diagnostic methods, and treatments. Methods We discuss the approach used in our institution, where we have treated 48 patients with enchondromas of the hand between 1996 and 2016. Our technique of treatment, which has remained the same over 2 decades, comprises the use of curettage, high-speed burr, and autologous bone graft (harvested with a minimally invasive technique, using a Craig biopsy needle). Results Pain and fractures were the most common symptoms leading the patients to consultation, at frequencies of 33.3% and 31.3%, respectively. A total of 27.1% of the cases were asymptomatic, and their lesions were discovered incidentally. The mean age was 34.4 years (SD = 12.9 years). Tumors were more frequently presented in the ulnar side of the hand, in the fifth ray (41.5%) and in the proximal bones (in the proximal phalanges [43.8%], and in the metacarpal [33.3%]). The size of the tumors ranged from 0.2 cm2 to 5.7 cm2, with a mean of 1.7 cm2 (standard deviation [SD] = 1.0 cm2) and were not associated with fracture (p = 0.291). Fracture was also not associated with any of the symptoms, neither with the age of the patients (p = 0.964). After the treatment, most patients achieved full range of motion (91.7%), with good integration of the bone graft. Three patients presented deficit in range of motion (6.3%) and the incidence of complications was also 6.3% (3 patients). At the end, after the needed surgical revisions, these three patients also recovered full function. They achieved full bone graft integration, regained full range of motion and returned to work. There was no tumor recurrence case during the follow-up period evaluated. For all cases, no donor site complications occurred. Conclusion Our method of treatment has consistently provided good outcomes, with only a few minor complications. Therapeutic level of evidence: IV.


Resumo Objetivo Os encondromas são os tumores mais comuns dos ossos da mão, com uma grande variedade de abordagens terapêuticas. O presente artigo apresenta as características dos tumores, métodos diagnósticos e tratamentos. Métodos Discutimos a abordagem da nossa instituição, onde tratamos 48 pacientes com encondromas da mão, entre 1996 e 2016. Nossa técnica de tratamento, que permanece a mesma ao longo de duas décadas, compreende o uso de curetagem, esmeril de velocidade e enxerto ósseo autólogo (retirado com uma técnica minimamente invasiva, usando uma agulha de Craig). Resultados A dor e as fraturas foram os sintomas mais comuns, levando os pacientes à consulta, nas frequências de 33,3% e 31,3%, respectivamente. Um total de 27,1% dos casos era assintomático, e suas lesões foram descobertas incidentalmente. A média de idade foi de 34,4 anos (desvio padrão [DP] = 12,9 anos). Os tumores foram mais frequentemente encontrados no lado ulnar da mão, no quinto raio (41,5%), e nos ossos proximais (nas falanges proximais [43,8%] e no metacarpo [33,3%]). O tamanho do tumor variou de 0,2 cm2 a 5,7 cm2, com média de 1,7 cm2 (DP = 1,0 cm2) e não foi associado à fratura (p = 0,291). A fratura também não foi associada a nenhum dos sintomas, e nem à idade dos pacientes (p = 0,964). Após o tratamento, a maioria dos pacientes alcançou amplitude completa de movimento (91,7%), com boa integração do enxerto ósseo. Três pacientes apresentaram déficit no arco de movimento (6,3%) e a incidência de complicações também foi de 6,3% (3 pacientes). No final, após as revisões cirúrgicas necessárias, esses três pacientes também recuperaram a função completa. Eles tiveram a integração total do enxerto ósseo, recuperaram toda a amplitude de movimento e retornaram ao trabalho. Não houve nenhum caso de recorrência do tumor durante o período de acompanhamento avaliado. Em nenhum dos casos ocorreram complicações no local doador. Conclusão O nosso método de tratamento forneceu consistentemente bons resultados, com apenas algumas complicações menores. Nível terapêutico de evidência: IV.


Subject(s)
Humans , Male , Female , Adult , Pain , Biopsy , Bone and Bones , Chondroma , Bone Transplantation , Curettage , Hand Bones , Fractures, Bone , Hand , Neoplasms
5.
Acta ortop. mex ; 33(5): 325-328, sep.-oct. 2019. tab, graf
Article in Spanish | LILACS | ID: biblio-1284965

ABSTRACT

Resumen: El síndrome de Maffucci se caracteriza por la presencia de múltiples encondromas y hemangiomas que pueden afectar tejidos blandos y otros órganos. El riesgo de transformación maligna de las lesiones es de 100% durante la vida del individuo, siendo el condrosarcoma el tumor maligno más frecuentemente asociado. Se presenta el caso de un hombre de 44 años de edad con diagnóstico de síndrome de Maffucci, el cual desarrolló un doble primario sincrónico: condrosarcoma y sarcoma fusocelular de alto grado multicéntrico de región escapular y tricipital, fue tratado con desarticulación interescapulotorácica, mostró progresión acelerada y enfermedad pulmonar. Existen otras neoplasias asociadas al síndrome de Maffucci tales como adenocarcinoma de páncreas, tumores mesenquimales de ovario, gliomas, astrocitomas y tumores de la pituitaria. Por lo que resulta muy interesante reportar la asociación infrecuente entre un sarcoma fusocelular y un condrosarcoma secundario en pacientes con síndrome de Maffucci. El seguimiento en este grupo de pacientes es complejo y se basa en la búsqueda intencionada de lesiones con crecimiento acelerado, prestando atención en lesiones de crecimiento progresivo, síntomas clínicos o datos radiológicos de malignidad.


Abstract: Maffucci syndrome is characterized by the presence of multiple enchondromes and hemangiomas that can affect soft tissues and other organs. The risk of malignant transformation of lesions is 100% during the life of the individual, with chondrosarcoma being the most frequently associated malignant tumor. We present the case of a 44-year-old man diagnosed with Maffucci syndrome who developed a synchronous double primary: chondrosarcoma and high-grade multicenter fusocellular sarcoma of scapular and tricipital region, was treated with disarticulation interscapule-thoracic, presented accelerated progression and lung disease. There are other neoplasms associated with Maffucci syndrome, such as pancreatic adenocarcinoma, mesenchymal ovarian tumors, gliomas, astrocytomas and pituitary tumors. It is therefore very interesting to report the uncommon association between fusocellular sarcoma and secondary chondrosarcoma in patients with Maffucci syndrome. Follow-up in this group of patients is complex and is based on the intentional search for accelerated growing lesions, paying attention to progressive growth injuries, clinical symptoms or radiological malignancy data.


Subject(s)
Humans , Adult , Bone Neoplasms/surgery , Bone Neoplasms/complications , Adenocarcinoma/surgery , Adenocarcinoma/complications , Chondrosarcoma/surgery , Chondrosarcoma/complications , Enchondromatosis/surgery , Enchondromatosis/complications
6.
Indian J Dermatol Venereol Leprol ; 2019 May; 85(3): 291-294
Article | IMSEAR | ID: sea-192495

ABSTRACT

Maffucci syndrome is a rare nonhereditary disorder comprising of lymphovascular malformations and multiple enchondromas, which may be associated with several internal malignancies. This report describes a new association of Maffucci syndrome with pedal synovial sarcoma. Our case is also remarkable as lymphangioma circumscriptum is the sole lymphovascular component, which has been rarely reported. The aim of this report is to generate awareness about this rare condition and also highlight the importance of screening for malignancies in this disorder.

7.
The Journal of the Korean Orthopaedic Association ; : 447-451, 2019.
Article in Korean | WPRIM | ID: wpr-770081

ABSTRACT

This case report describes the unusual occurrence of a flexor digitorum profundus avulsion secondary to an enchondroma of the distal phalanx of the middle finger. The enchondroma was treated by simple curettage with an autogenous bone graft harvested from the olecranon. The avulsed bone fragment was reattached to the distal phalanx using the pull-out suture technique. Bony union and full function of the digit were achieved.


Subject(s)
Chondroma , Curettage , Fingers , Olecranon Process , Suture Techniques , Transplants
8.
Article | IMSEAR | ID: sea-187367

ABSTRACT

Background: A bone tumor is a neoplastic growth of tissue in bone. Abnormal growths found in the bone can be either benign (noncancerous) or malignant (cancerous). Aims and objectives: The purpose of this study was to evaluate the role of MRI in cases of primary malignant bone tumors and MRI characteristics of different primary malignant bone tumors, to compare the imaging findings with surgical and gross pathological findings, Staging of tumor on MRI, correlating them with operative and histopathological findings. Materials and methods: This was a prospective study done in Department of Radiodiagnosis of NRIGH comprising of 40 patients 21 male and 19 female who were suspected or proven cases of the malignant bone tumor. Plain radiographs in AP and Lateral views (including the adjacent joint) were taken in all cases. The primary pulse sequences included T1 and T2 WI using spine echo and gradient echo techniques with TR of 600 msec. and TE 30msec. for T1WI and TR of 2740 msec. and TE of 85 msec. for T2 WI . The MR morphology was correlated with surgical and histopathological features. Results: The study “Multiplanar MR Imaging of primary malignant bone tumors with surgical and histopathological correlation” comprised of 40 patients in a two year period starting from august 2010 to September 2012 the age ranged from 8 years to 71 years (mean 40 years). There were 21 males and 19 females. Conclusion: MRI in combination with plain radiography is an excellent modality for evaluation of the musculoskeletal pathologies especially differentiating a malignant from a benign lesion. The multiplanar imaging capabilities place a major role in delineation of tumour extent in to the bone and Karuna V, R Vikash Babu. MR imaging of primary malignant bone tumors with surgical and histopathological correlation. IAIM, 2019; 6(10): 8-21. Page 9 soft tissues with high contrast and resolution with additional information of neurovascular bundle involvement, joint involvement and staging.

9.
Journal of the Korean Shoulder and Elbow Society ; : 100-104, 2017.
Article in English | WPRIM | ID: wpr-770797

ABSTRACT

Enchondromas generally occur in the hand and uncommonly in the long bones. Because enchondromas are usually asymptomatic, most are discovered during diagnostic radiology for another disease. Here, we describe a case of enchondroma in the right humerus in a 79-year-old female patient with concomitant rotator cuff tear arthropathy. The patient was initially hospitalized for prolonged pain and pseudoparalysis of the right shoulder. The condition, which was histologically confirmed as an enchondroma in the proximal humerus, was treated with curettage and reverse total shoulder arthroplasty. In this case report, we present a rare case of an enchondroma with combined rotator cuff tear arthropathy.


Subject(s)
Aged , Female , Humans , Arthroplasty , Chondroma , Curettage , Hand , Humerus , Rotator Cuff , Shoulder , Tears
10.
Rev. Asoc. Argent. Ortop. Traumatol ; 82(3): 189-194, 2017. []
Article in Spanish | LILACS, BINACIS | ID: biblio-869367

ABSTRACT

Introducción: los encondromas solitarios son los tumores óseos más comunes de la mano. Aproximadamente el 40% compromete esta extremidad, con predilección por los rayos cubitales y las falanges proximales. El riesgo de transformación maligna a condrosarcoma es del 1% y el de recurrencia, del 2-15%. Se describen la experiencia y los resultados de un importante número de pacientes con un seguimiento a largo plazo. Materiales y Métodos: Estudio descriptivo, retrospectivo, de tipo serie de casos. Se seleccionaron pacientes con diagnóstico confirmado de encondroma solitario de la mano, que fueron manejados mediante resección con curetaje del tumor más aplicación de injertos autólogos de cresta ilíaca o radio. Después del tratamiento quirúrgico, se evaluaron la función, mediante la clasificación de Takigawa, los resultados radiográficos y la frecuencia de complicaciones o recidivas. Resultados: Se incluyeron 19 pacientes con un seguimiento posoperatorio promedio de 11 años. De acuerdo con la clasificación de Takigawa, la función fue excelente en 16 pacientes (84,2%) y buena en 3 (15,7%). Un paciente presentó una infección del sitio operatorio incisional superficial, con resolución completa. No hubo recidivas. Conclusiones: En los pacientes evaluados, los resultados funcionales y radiológicos fueron buenos después de la cirugía. Los encondromas plantean el riesgo de fracturas patológicas, recidiva y, en menor proporción, de transformación maligna; sin embargo, esto no ocurrió en ninguno de los casos. Se describe una opción de manejo quirúrgico, sencilla con buenos y excelentes resultados a largo plazo.


Introduction: Isolated enchondromas are the most common tumors of the hand. Approximately 40% affect this upper extremity, with preference for cubital rays and proximal phalanges. Risk of malignant transformation to chondrosarcoma is 1% and the risk of recurrence ranges from 2 to 15%. Our experience and results with a large number of patients with a long-term follow-up are described. Methods: Descriptive, retrospective, case series study. Patients with diagnosis of isolated enchondroma of the hand that were treated with tumor resection, curettage and iliac crest or radius autograft placement were included. After surgical treatment, hand function was assessed using the Takigawa classification, radiological results and frequency of complications or recurrence were evaluated. Results: Nineteen patients with a mean follow-up of 11 years were included. According to the Takigawa classification, function was excellent in 16 patients (84.2%) and good in 3 (15.7%). One patient had an incisional superficial surgical site infection that resolved completely. No cases of recurrence were identified. Conclusions: Good functional and radiological results were obtained after surgical treatment. Enchondromas can pose the risk of pathological fractures, recurrence and, in a lesser degree, malignant transformation; however, none of these complications were identified. The results of a simple surgical treatment option with good and excellent long-term results are described.


Subject(s)
Humans , Middle Aged , Chondroma/surgery , Hand , Bone Neoplasms/surgery , Retrospective Studies , Follow-Up Studies , Treatment Outcome
11.
Clinics in Shoulder and Elbow ; : 100-104, 2017.
Article in English | WPRIM | ID: wpr-202501

ABSTRACT

Enchondromas generally occur in the hand and uncommonly in the long bones. Because enchondromas are usually asymptomatic, most are discovered during diagnostic radiology for another disease. Here, we describe a case of enchondroma in the right humerus in a 79-year-old female patient with concomitant rotator cuff tear arthropathy. The patient was initially hospitalized for prolonged pain and pseudoparalysis of the right shoulder. The condition, which was histologically confirmed as an enchondroma in the proximal humerus, was treated with curettage and reverse total shoulder arthroplasty. In this case report, we present a rare case of an enchondroma with combined rotator cuff tear arthropathy.

12.
The Journal of the Korean Orthopaedic Association ; : 85-90, 2016.
Article in Korean | WPRIM | ID: wpr-649177

ABSTRACT

PURPOSE: We analyzed outcomes after management of enchondroma involving short tubular bones of the hand and foot by curettage and grafting using allogenic bone or bone substitutes. MATERIALS AND METHODS: Twenty-two patients (allogenic bone 15 and bone substitutes 7 patients) were recruited. Clinical results were assessed by pain, cosmetic problem, range of motion of joint and the power of grasp. Radiographic outcomes were analyzed by degree of bone defect. RESULTS: Clinically, 19 patients were classified as excellent and 3 patients as good. Three patients with K-wire fixation had pain with local irritation, which was easily controlled by removal of the K-wires. There were no complications including deep infection, delayed or nonunion, refracture. Radiographically, 20 cases were classified as group 1 (bone defect smaller than 3 mm) and the 2 remaining cases were classified as group 2 (bone defect 4-10 mm). CONCLUSION: Curettage and graft using allogenic bone or bone substitute is an effective modality of treatment for enchondroma involving short tubular bones of the hand and foot. When combined with pathologic fracture, early surgical management could shorten duration of immobilization. Surgical management might be considered for the lesion involving the foot when discovered because of high incidence of pathologic fracture.


Subject(s)
Humans , Bone Substitutes , Chondroma , Curettage , Foot , Fractures, Spontaneous , Hand Strength , Hand , Immobilization , Incidence , Joints , Range of Motion, Articular , Transplants
13.
Article in English | IMSEAR | ID: sea-174410

ABSTRACT

In humans sometimes abnormal intracartilaginous mode of ossification can lead to formation of a bony lesion referred to as Enchondroma. Enchondroma can present as a solitary lesion that involves metacarpals, metatarsals, and phalanges in most of the cases or as multiple lesions. We present a case of a 28 year old male who presented with pain in his forearm and digits on both sides. The pain was of mild nature .Rest of the general and skeletal survey was normal. He was followed with radiographs which revealed multiple enchondromata bilaterally. On history there was no familial history of similar or related disease.

14.
Journal of the Korean Society for Surgery of the Hand ; : 99-106, 2012.
Article in Korean | WPRIM | ID: wpr-73062

ABSTRACT

PURPOSE: The purpose of this study was to evaluate the effectiveness of contact cryotherapy as an adjuvant therapy after intralesional curettage and autoiliac bone graft of enchondromas of the hand. MATERIALS AND METHODS: Thirty seven cases in 30 patients (17 males, 13 females) with enchondromas of the hand who underwent curettage, contact cryotherapy and autoiliac bone graft between July 2004 and March 2010 were reviewed with a minimum follow-up of 1 year. Radiologic evaluations were done periodically. Mean follow-up period was 26 months (range: 12-54 months). The radiologic results were evaluated according to the degree of new bone formation based on the Tordai's criteria. RESULTS: According to the Tordai's criteria, 33 cases (89%) were group I, and 4 cases (11%) were group II. There was no case of group III, which meant recurrence. Bone healing was achieved at average 4.8 months (range: 4-5.3 months) after the operation. There was no cryotherapy-related complication such as pathologic fracture, bone necrosis and skin necrosis during the follow-up periods. CONCLUSION: We suggest that the contact cryotherapy can be used as an effective adjuvant therapy for treatment of enchondroma of the hand without complications.


Subject(s)
Humans , Male , Chondroma , Cryotherapy , Curettage , Follow-Up Studies , Fractures, Spontaneous , Hand , Necrosis , Osteogenesis , Recurrence , Skin , Transplants
15.
The Journal of the Korean Bone and Joint Tumor Society ; : 87-90, 2010.
Article in Korean | WPRIM | ID: wpr-166065

ABSTRACT

Enchondroma is a benign tumor mainly developed in the hand and uncommon in the foot. Even if it is in the foot, most are in the phalanges and distal metatarsals of the foot. Enchondroma in the calcaneus is very rare. A 44-year-old male suffered from left heel pain for several months, authors treated it with curettage and bone graft, it was histologically confirmed as an enchondroma in the calcaneus. The authors presented a rare case presentation of an enchondroma in the calcaneus with pain.


Subject(s)
Adult , Humans , Male , Calcaneus , Chondroma , Curettage , Foot , Hand , Heel , Metatarsal Bones , Transplants
16.
Rev. colomb. reumatol ; 16(3): 315-317, jul.-sep. 2009. ilus
Article in Spanish | LILACS | ID: lil-636805

ABSTRACT

El encondroma solitario es un tumor cartilaginoso de naturaleza benigna, habitualmente asintomático, que se presenta entre la tercera y cuarta década de la vida. Se reporta a continuación un caso de una mujer de 60 años con encondroma solitario en fémur izquierdo, confirmando su diagnóstico mediante una resonancia nuclear magnética.


Solitary enchondroma is a benign cartilaginous tumor, usually asymptomatic, presents between the 3 and 4 decade. We report a 60 years old woman with solitary enchondroma in left femur, confirming the diagnosis with magnetic resonance imaging.


Subject(s)
Humans , Female , Middle Aged , Chondroma , Femur , Neoplasms , Women , Magnetic Resonance Spectroscopy , Cartilage , Diagnosis
17.
The Journal of the Korean Orthopaedic Association ; : 294-300, 2009.
Article in Korean | WPRIM | ID: wpr-656182

ABSTRACT

PURPOSE: Intramedullary cartilage forming tumors in the meta-diaphysis of the long bones can represent an enchondroma or a low-grade chondrosarcoma, with the latter requiring adequate surgical treatment. However, these two lesions have overlapping clinical and histological features and so they pose a diagnostic and therapeutic dilemma. The purpose of this study was to analyze the clinical outcome and to determine the relevant clinical and radiographic parameters for deciding on the treatment for these tumors. MATERIALS AND METHODS: We conducted a retrospective review of 73 patients who were treated for enchondroma or low-grade chondrosarcoma that was located in the metaphysis or diaphysis of the bones. There were 20 men and 53 women with an average age of 49 years (range: 18-80). The locations were the proximal humerus (n=34), distal femur (24), proximal femur (6), proximal tibia (3), proximal fibula (2), humerus shaft (2) and femur shaft (2). 41 patients were treated surgically and 32 patients were simply observed based on the following parameters at presentation; the presence of pain, the tumor length and radiographic evidence of endosteal erosion. RESULTS: All of the 32 patients who were initially observed had no evidence of disease progression at the last follow-up (average: 3.2 years, range: 1.0-14.9). Forty (98%) of the surgically treated patients showed no recurrence at the the last follow-up (average: 4.3 years, range: 1.0-14.0). CONCLUSION: The presence of pain, tumor length and radiographic evidence of endosteal erosion should be considered to determine the best course of treatment for intramedullary cartilage forming tumors in the meta-diaphysis of the long bones. With the appropriate selection of the patients, these tumors can be successfully treated nonoperatively.


Subject(s)
Female , Humans , Male , Cartilage , Chondroma , Chondrosarcoma , Decision Making , Diaphyses , Disease Progression , Femur , Fibula , Follow-Up Studies , Humerus , Recurrence , Retrospective Studies , Tibia
18.
Orthopedic Journal of China ; (24)2006.
Article in Chinese | WPRIM | ID: wpr-548548

ABSTRACT

[Objective]To report the results of treatment of enchondroma of the hand with curettage and porous bioceramic bone grafting. [Methods]Fifteen patients with digital enchondroma were reviewed.The average follow-up period was 30 months.The final function and radiographic appearance of the surgically treated digits were analyzed.[Results]At final evaluation the bony incorporation was uneventful in all patients.The mean functional Muskuloskeletal Tumor Society Score was 29.Radiographs showed apparent partial absorption of bioceramic bone in only two patients.All digits achieved full range of motion after surgery.No complication was found.[Conclusion]Porous bioceramic bone is safe and effective as a bone-filling substance after curettage of enchondroma of the hand.

19.
The Journal of the Korean Orthopaedic Association ; : 44-49, 2004.
Article in Korean | WPRIM | ID: wpr-648421

ABSTRACT

PURPOSE: Retrospectively, to evaluate the result of treatment by curettage only, enchondroma of the digits. MATERIALS AND METHODS: Fifty-nine cases in 30 patients (male 11, female 19), from July 1997 to Febuary 2002, were reviewed with a minimum follow up of 1 year. Thirty patients were treated for enchondroma of the digits (including Ollier's disease 9, and Maffucci syndrome 2) by curettage only, and the degree of healing was evaluated radiologically. The average duration of follow up was 28.6 months (12-65 months). RESULTS: The radiologic results were evaluated according to the degree of new bone formation by the criteria suggested by Tordai. Group I achieved 79.7% overall and 89.5% for solitary enchondroma, meaning complete healing with normal cortical thickness and a bone defect of less than 3 mm. The average duration of consolidation was 12.4 months, and 8.1months for solitary enchondorma. No recurrence or other complication occured. CONCLUSIONS: Curettage alone is a good treatment option for enchondroma of the digits as comparing with autogenous bone graft, which has the disadvantages of pain, infection, and immobilization.


Subject(s)
Female , Humans , Chondroma , Curettage , Enchondromatosis , Follow-Up Studies , Immobilization , Osteogenesis , Recurrence , Retrospective Studies , Transplants
20.
The Journal of the Korean Orthopaedic Association ; : 45-50, 2002.
Article in Korean | WPRIM | ID: wpr-653949

ABSTRACT

PURPOSE: To evaluate the effectiveness of treatments for enchondromas of the hand with heterograft bone substitute instead of bone autograft. MATERIALS AND METHODS: We reviewed the radiographs of 15 patients that were followed for a minimum of 6 months. From January 1995 to May, 2000, fifteen patients that were treated with heterograft bone and could be followed-up for at least 6 months were retrospectively studied. Clinical, radiological and histological results were evaluated. RESULTS: Clinically excellent in 5, good in 10. Radiologic result was 12 in Group 1, 3 in Group 2, the average consolidation duration was 8 months (5-11 months). The typical histologic findings of enchondroma by intraoperative specimens were hyaline cartilage, myxoid degeneration, calcification, and enchondral ossification. Grafted heterograft bone was incorporated via physiologic remodelling without significant problems. No signigicant complications occurred. CONCLUSION: We believe that heterograft bone is a good treatment option for enchondromas of the hand, given the disadvantages of bone autografts or allografts.


Subject(s)
Humans , Allografts , Autografts , Bone Substitutes , Chondroma , Hand , Heterografts , Hyaline Cartilage , Retrospective Studies , Transplants
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